Журнал включен в российские и международные библиотечные и реферативные базы данных
РИНЦ (Россия)
RINZ (RUSSIA)
Регистрационное агентство DOI (США)
DOI Registration Agency (USA)
Эко-Вектор (Россия)
Eco-Vector (Russia)
Ulrichsweb (Ulrich’s Periodicals Director

Brain and gut rhythm regularity and level of happiness

DOI: https://doi.org/10.29296/25879979-2022-05-03
Download full text PDF
Issue: 
5
Year: 
2022

K.A. Shemerovsky(1), V.P. Ganapolsky(2), M.A. Kharin(1)
¹-Private Educational Institution of Higher Education «Saint-Petersburg Medical-Social University»
2-The Military Medical Academy named after S.M. Kirov

The dependence of the level of happiness on the observance of the circadian rhythm of the brain (according to bedtime) and the circadian rhythm of the intestine (according to the habit of morning defecation) was studied in 156 young doctors (112 women and 44 men) aged 18–24 years. A validated questionnaire was used for weekly monitoring of bowel rhythm and setting bedtime, as well as for determining the level of happiness on a 10-point visual analog scale. A regular bowel rhythm with a stool frequency of at least 7 times a week (Euenteria) was found in 78 physicians (50%) and an irregular bowel rhythm with a frequency of 3–6 times a week (Bradyenteria) was found in 78 physicians (50% of respondents). It was found that 56% of the surveyed medical students did not comply with the regime of timely (up to 24:00 h) bedtime, and persons with euenteria were less likely to disrupt this rhythm than those with bradyenteria. In persons with bradyenteria, the absence of the habit of morning defecation was almost 3 times more common than in persons with euenteria. The level of happiness in individuals with a daily bowel rhythm and timely bedtime was 1.4 times higher than in individuals with a stool frequency of 3–4 times a week (defecation every other day) and late bedtime.

Keywords: 
regular bowel rhythm
euenteria
morning bowel movement habit
irregular rhythm
bradyenteria
falling asleep before midnight
after midnight.Key words: regular bowel rhythm
euentery
morning defecation habit
irregular rhythm
bradyentery
falling asleep before midnight
after midnight



It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Shemerovsky K.A., Mitreikin V.F., Uspenskaya Y.K. Dependence of the level of drug intake on the regularity of the circadian rhythm of the intestine. Bulletin of the Russian Military Medical Academy. 2012, №1 (37), С. 112-115.
  2. Bochkarev MV, Korostovtseva LS, SV Sviryaev SV, Ragozin ON Sleep-wake cycle. Chronobiology and chronomedicine. Moscow, PFUR, 2018, P. 550-581.
  3. Shemerovsky K.A. Chronobiological strategy for treatment of patients with constipation. Chronobiology and chronomedicine. Moscow, PFUR, 2018, P. 804-816.
  4. Poluektov M.G. Insomnia. Chapter 11. Somnology and sleep medicine. National manual in memory of A.M. Vein and J.I. Levin (ed. by M.G. Poluektov). Moscow. Medforum, 2016, P. 298-318.
  5. Poluektov M.G. Disorders of the sleep-wake cycle. Chapter 14. A.M. Vein and J.I. Levin National Manual (edited by M.G. Poluektov). Moscow. Medforum, 2016, P. 376–389.
  6. Poluektov M.G. Sleep and the digestive system. Chapter 26. A.M. Vein and J.I. Levin National Manual (ed. by M.G. Poluektov). Moscow. Medforum, 2016, P. 615–622.
  7. Shemerovsky K.A. Bradyenteric syndrome as an inducer of obesity in cardiology patients. «Therapeutic Aspects of Cardiology Practice,» XIII Conference of the Eurasian Association of Physicians, November 26–27, 2021, P.59–61.
  8. Shemerovsky K.A. Mental health and regularity of evacuatory bowel function. Academic notes of St. Petersburg State Medical University named after acad. I.P. Pavlov, 2009, №4, 136–139.
  9. Shemerovsky K.A. Chronomedical approach to the correction of constipation. Therapy, 2020, Vol. 6, No. 1 (35). С. 136–140.
  10. Shemerovsky K.A. Constipation - a risk factor for colorectal cancer. Clinical Medicine. 2005. 83 (12): 60–64.
  11. Ledentsova S. S., Gulyaev N. I., Sitkin S. I., Seliverstov P. V. Acne as extraintestinal manifestation of celiac disease. Approaches to therapy. Medical Advice. 2020; 21: 126–135.
  12. Bowe WP, Logan AC. Acne vulgaris, probiotics and the gut-brain-skin axis – back to the future? Gut Pathog. 2011; 3(1): 1. Published 2011 Jan 31. doi:10.1186/1757-4749-3-1
  13. Wang SX, Wu WC. Effects of psychological stress on small intestinal motility and bacteria and mucosa in mice. World J Gastroenterol. 2005; 11(13): 2016–2021. doi:10.3748/wjg. v11.i13.2016
  14. Strickler A, Kolmer JA, Schamberg JF: Complement fixation in acne vulgaris. J Cutaneous Dis. 1916, 34: 166–78.
  15. Juhlin L, Michalsson G. Fibrin microclot formation in patients with acne. Acta Derm Venereol. 1983;63(6):538–540.
  16. Yuksel M, ulfer G. Measurement of the serum zonulin levels in patients with acne rosacea. J Dermatolog Treat. 2022; 33(1): 389–392 doi:10.1080/09546634.2020.1757015
  17. Ketron LW, King JH: Gastrointestinal findings in acne vulgaris. JAMA. 1916, 60: 671–75.
  18. Zhang H, Liao W, Chao W, et al. Risk factors for sebaceous gland diseases and their relationship to gastrointestinal dysfunction in Han adolescents. J Dermatol. 2008; 35(9): 555–561. doi:10.1111/j.1346-8138.2008.00523.x
  19. Khalif IL, Quigley EM, Konovitch EA, Maximova ID. Alterations in the colonic flora and intestinal permeability and evidence of immune activation in chronic constipation. Dig Liver Dis. 2005; 37(11): 838–849. doi:10.1016/j.dld.2005.06.008
  20. Attaluri A, Jackson M, Valestin J, Rao SS. Methanogenic flora is associated with altered colonic transit but not stool characteristics in constipation without IBS. Am J Gastroenterol. 2010;105(6):1407–1411. doi:10.1038/ajg.2009.655
  21. Maes M, Kubera M, Leunis JC. The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression. Neuro Endocrinol Lett. 2008;29(1):117–124.
  22. Hillila MT, Hamaainen J, Heikkinen ME, Farkkia MA. Gastrointestinal complaints among subjects with depressive symptoms in the general population. Aliment Pharmacol Ther. 2008;28(5):648–654. doi:10.1111/j.1365-2036.2008.03771.x
  23. Gorard DA, Gomborone JE, Libby GW, Farthing MJ. Intestinal transit in anxiety and depression. Gut. 1996;39(4):551–555. doi:10.1136/gut.39.4.551